Other processes that are altered mainly in COVID-19 non-ICU patients (cluster 7, Fig. 5B) refer to endothelial cell integritysuch as VASNa factor downregulated during vessel repair [50], the vascular endothelial cadherin CDH5and the regulation of glucose metabolism by the adipose tissueincluding Adiponectin (ADIPOQ) and Retinol-Binding Protein 4 (RBP4). The gene discussed is CDH5; the disease is COVID-19.