TSPO and glycogen storage disease VI: Our study is the first to fully validate TSPO expression as a biologically relevant imaging target for ZIKV neuroinflammatory disease and to demonstrate that elevated brain TSPO expression in late ZIKV disease is conferred by two mechanisms: (1) increased TSPO expression on myeloid cells, primarily infiltrating monocytes and brain-resident microglia; and (2) overwhelming increase in numbers of TSPO-expressing immune cells, mainly of granulocytes and T cells.