Cluster 1 was characterized by upregulation of tumor-suppressing genes: HNF1B, CCNDBP1, PATJ, EPB41L3, MARVELD2, PTEN in conjunction with cell-cycle genes – GSPT1, GPR19, EAPP, KIT, CDKL1, and stem cell markers – RBBP5, NANOG, NCSTN, ERG, including quiescent stem cell markers—FOXP1, SMARCA2 (Fig. 2B, C, Fig. S4B, Fig. S4G). This evidence concerns the gene PTEN and neoplasm.