CDKN1A and leukemia: Importantly, the exogenous expression of p21 cDNA in p21-depleted MDMs (p21TD + sh3’UTRp21) restored the phagocytic activity of these complemented MDMs as compared to that of control or p21-depleted cells (Co.TD or sh3’UTRp21) (Supplementary Fig. 5k, l), further corroborating the specific key role of p21 in promoting the phagocytosis of leukemia cells by macrophages.