Neither a broad-spectrum caspase inhibitor (ZVAD) (Fig. 1c, d) nor recombinant human annexin V (Supplementary Fig. 1d, e), which impair apoptosis and the engulfment of phosphatidylserine-exposing and dying cells (as shown in cis-platinum (CDDP)-treated cells (Supplementary Fig. 1d, e)), respectively, increased or reduced the engulfment of Jurkat cells and primary AML blasts by macrophages, thus excluding the possibility that the detection of tumor cell phagocytosis was associated with the clearance of dying tumor cells by efferocytosis19. Here, ANXA5 is linked to acute myeloid leukemia.