In accordance with the previously demonstrated role of ROCK-dependent signaling pathways in phagocytosis18, MDM engulfment of leukemia cells and cell lines may depend on ROCK activity, as the pharmacological inhibition of ROCK kinase activity with Y27632 (as indicated by inhibition of myosin light chain 2 (MLC2) phosphorylation on serine 19 (MLC2S19*) (Supplementary Fig. 1b)) abolished Jurkat cell phagocytosis (Supplementary Fig. 1c). This evidence concerns the gene MYL2 and leukemia.