MOS and neoplasm: No increased expression of these markers was detected in mCD45+mF4/80+ mouse macrophages sorted on d 21 or 35 after Mo transfer from the spleen or BM of mCherry+ MOLT4 cell-engrafted or tumor-free NSG mice adoptively infused with Co.TD-Mos or p21TD-Mos as compared to corresponding cells sorted from control mice (Supplementary Fig. 17), suggesting that the observed bystander proinflammatory activation of human TAMs (Fig. 4e, f) mainly depended on factors secreted by the p21TD-Phago+ MDMs.