MOS and neoplasm: In contrast to MDMs sorted from tumor-free NSG mice infused with Co.TD-Mos or p21TD-Mos (Fig. 4d), Phago- MDMs sorted from mCherry+ MOLT4 cell-engrafted NSG mice injected with p21TD-Mos exhibited a significant increase in iNOS expression on d 35 (Fig. 4e), suggesting that Phago+ MDMs can support the proinflammatory reprogramming of surrounding TAMs in the TME.