OCM and cutaneous melanoma: Indeed, we found that MGH-CP1 markedly inhibits the growth of OMM1.3 (GNAQ mt) and Mel202 (GNAQmt) with IC50 around 4 μM but has little anti-proliferative effects on YAP-independent OCM1 (BRAFmt), and cutaneous melanoma cell lines A375 (BRAFmt), SKMEL2 (NRASmt), SK-MEL28 (BRAFmt) and SK-MEL31(RAS/BRAFwt) cells with IC50 > 30 μM (Fig. 3h).