In the retinas of mice with diabetic retinopathy, LATS and TAZ were increased, and p-MST and p-YAP were significantly decreased.291 In addition, in patients with Sveinsson’s chorioretinal atrophy, the Tyr421His mutation in TEAD1 has been found, and this mutant Tyr421His TEAD1 has a compromised interaction with YAP.148,292 Moreover, MST2 but not MST1 was identified as a factor that causes retinal detachment-induced photoreceptor cell death. This evidence concerns the gene YAP1 and diabetic retinopathy.