D/R@Ang2-Lip+Au, a doxorubicin- and YAP-siRNA-loaded cationic liposome, was able to effectively inhibit glioblastoma.369 In addition, another YAP-siRNA-lipid nanoparticle repressed hepatocellular carcinoma in a mouse model.370 In addition to cancer treatment, YAP-siRNA was effective in treating posterior segment neovascularization-related ocular diseases.371 In addition to siRNA, shRNA is another common tool for genetic inhibition. The gene discussed is YAP1; the disease is hepatocellular carcinoma.