In addition to retinal-related diseases, the heterozygous inactivation of YAP1, which decreases the expression of YAP1 protein in lens epithelia, results in cataracts with lens epithelial cell defects.294 Moreover, NF2 deficiency in the lens epithelium in mice could lead to a cataract phenotype.64 The gene discussed is YAP1; the disease is cataract.