Subsequently, an analysis of 120 CRC tissue chip specimens by IHC revealed that the expression of FMR1 was positively correlated with that of EGFR and METTL3 (Fig. 6g, h, r = 0.799, P < 0.001; r = 0.656, P < 0.001). The gene discussed is METTL3; the disease is colorectal carcinoma.