MTOR and colorectal carcinoma: Interestingly, there was no obvious change of p-mTOR and total mTOR (unphosphorylated protein) expression in CRC cells overexpressing or silencing Myo1b (Fig. 3B, C, Fig. S5a, b), implying that Myo1b might participate in autophagy by affecting the autophagosome-lysosome fusion not the beginning of autophagy in CRC cells.