In the KEGG pathway enrichment analysis, the results indicated that EZW exerted its effect on HCC mainly through the following pathways: “Cell cycle (ko04110)”, “Progesterone-mediated oocyte maturation (ko04914)”, “Steroid hormone biosynthesis (ko00140)”, “p53 signaling pathway (ko04115)”, “Cellular senescence (ko04218)”, “TNF signaling pathway (ko04668)”, “Metabolism of xenobiotics by cytochrome P450 (ko00980)”, “IL-17 signaling pathway (ko04657)”, “Hepatitis B (ko05161)”, and “FoxO signaling pathway (ko04068)” (Figure 7A). Here, TNF is linked to hepatocellular carcinoma.