[11] found that miR‐494 may play a role in epithelial‐mesenchymal transformation (EMT), tumor growth and metastasis of cholangiocarcinoma by negatively regulating WDHD1, and Zhou and Chen [17] demonstrated that STAT3 may affect DNA replication through transcriptional regulation of WDHD1. This evidence concerns the gene WDHD1 and neoplasm.