NTN4 and breast carcinoma: NTN4 has also been identified as a candidate breast cancer risk gene by colocalization analysis, where the C allele of SNP rs61938093 (r2 = 0.48 with the effect allele of rs113174754) at this region reduced NTN4 promoter activity and knockdown of NTN4 promoted breast cell proliferation and tumor growth [39].