APOB and obstructive sleep apnea syndrome: Moreover, the apo B/apo A-I ratio was higher in patients (1.39 ± 0.40) than in controls (0.99 ± 0.19, P < 0.001), and severe OSA patients (1.60 ± 0.47) had a higher apo B/apo A-I ratio than the mild OSA group (1.24 ± 0.28, P = 0.041) (Fig. 1c).