[211At]PSMA5 showed better tumor retention compared to [211At]PSMA1 and [211At]PSMA6 (30.6 ± 17.8, 12.4 ± 4.8 and 19.1 ± 4.5%ID/g at 3 h versus 40.7 ± 2.6, 8.7 ± 3.5 and 18.1 ± 2.2%ID/g at 24 h, respectively), whereas kidney excretion was superior in [211At]PSMA1 compared to [211At]PSMA5 and [211At]PSMA6. This evidence concerns the gene PSMA6 and neoplasm.