For example, we identified an association specific to asthma subgroup 5 “Musculoskeletal.” The lead variant was near osteoclast-stimulating factor 1 (OSTF1), a gene that interacts with fatty acid binding protein 4 (FABP4)96, which in turn regulates airway inflammation in experimental asthma97,98. This evidence concerns the gene FABP4 and asthma.