MYC and nasopharyngeal carcinoma: The strongest inverse correlation was observed for “nasopharyngeal cancer”, where MYC (MYC proto-oncogene, bHLH transcription factor), MAX (MYC associated factor X), and MXI1 (MAX interactor 1, dimerization protein) have positive enrichment scores in the disease-specific regulome signature (Fig. 3c and Supplementary Fig. 2) and these transcription factors have negative enrichment scores in the regulome signatures of approved drugs for the disease (Fig. 3d and Supplementary Fig. 3).