Therefore, we performed expression analysis of SHIP2 from HCC tissues and para-cancerous tissues, which showed mRNA- (Fig. 4H) and protein-level (Fig. 4I) reductions in SHIP2 expression and a negative correlation between SHIP2 expression and the LINC01468 level in 26 paired tumors and adjacent normal tissues from human NAFLD-associated HCCs (Fig. 4J). Here, INPPL1 is linked to metabolic dysfunction-associated steatotic liver disease.