The expression of lipogenic pathway enzymes such as SREBP1, FASN, ACLY, ACAC, and SCD1 was detected by qRT-PCR, and progressive induction of SREBP1, ACLY, FASN, ACAC, and SCD1 was observed in HCC tissues (Fig. 1E). Here, SREBF1 is linked to hepatocellular carcinoma.