We also found that the abundance of tau prions had a modest linear correlation with the abundance of Aβ prions (R2 = 0.2474; P = 0.0071) in people with DS (Fig. 1C), which was consistent with the AD neuropathology scores (SI Appendix, Fig. S2C) and biochemical measurements (SI Appendix, Fig. S2F). This evidence concerns the gene MAPT and Dravet syndrome.