ALB and preeclampsia: ALB, which encodes the most abundant protein in human blood, has been proved to be a strong predictor of preeclampsia,[41] especially can assess blood-brain barrier integrity and neuroinflammation in preeclampsia.[42] ALB is highly expressed in the serum of preeclampsia, and our study also shows that ALB expression is up-regulated in STB-EVs derived from preeclampsia.