Okadaic acid, a lipophilic marine toxin produced by several species of phytoplankton inhibits multiple protein phosphatases (PPs)—PP1, PP2A, PP2B, PP4, and PP5—and is associated with various systemic toxicities including cytotoxicity through apoptosis induction, neurotoxicity associated with tau protein hyperphosphorylation, immunotoxicity via modifications on interleukin-1 production, embryotoxicity, and even tumor promotion74. The gene discussed is MAPT; the disease is neoplasm.