The first variant, located in exon 11 of the PMS2 gene, is predicted to cause a truncated or absent protein due to a translational frameshift and has been reported in multiple patients with Lynch syndrome [11, 12] and children with CMMRD, including an 11‐year‐old with high‐grade glioma and osteosarcoma [9], a 14‐year‐old with colorectal adenocarcinoma [13] and a 7‐year‐old with glioblastoma and T‐cell lymphoma [14]. The gene discussed is PMS2; the disease is Lynch syndrome.