Also, the S1–S2 protocol evoked a close incidence of ventricular arrhythmias in whole hearts from the WT and Il-1r−/− groups (Figure 3D), 85.7% of the hearts from WT+Tc were affected, while among Il-1r−/−+Tc mice, 100%. The gene discussed is IL1R1; the disease is Ventricular arrhythmia.