Then, according to the type of CD19+ B cells, CD4+ T cells, pDCs and PBMC, 5142 DEGs of MS patients without treatment were obtained according to the standards of P < 0.05 and FC > 1.2 or 0 < FC < 1/1.2 (CD19+ B cells: 293 DEGs; CD4+ T cells: 2032 DEGs; pDCs: 1712 DEGs; PBMC: 1561 DEGs) (Table 1; Supplementary Table S1). This evidence concerns the gene CD19 and myeloid sarcoma.