found that DS patients (N=20) had higher concentrations of C-reactive protein (CRP) and interleukin-6 (IL-6) than NDS patients (N=42) (17), while another study found that tumor necrosis factor-α (TNF-α) and IL-6 levels were elevated in DS patients (N=17) compared to NDS patients (N=39). This evidence concerns the gene IL6 and Dravet syndrome.