In addition, the expression of MBP in enteric glial cells (76, 77) and 3A6/DR2a Tg animals’ partial immunodeficiency stemming from allelic exclusion, which is caused by the expression of a transgenic TCR, may promote the development of colitogenic T cells in 3A6/DR2a Tg mice. This evidence concerns the gene MBP and immunodeficiency disease.