The Candida albicans (C. albicans)-driven release of IL-7 from macrophages promotes aryl hydrocarbon receptor (AhR) and phospho-STAT3 (p-STAT3) binding at the IL-22 gene in ILC3s, which subsequently triggers the transcription of this cytokine for CAC formation in C. albicans AOM-DSS cancer model (19). This evidence concerns the gene IL22 and infectious otitis media.