OAS1 and Other metabolic disease: Next, to further determine which types of immune cells was dominant, we use UMAP for visualization, and those two metabolic pathways were observed to be significantly concentrated in monocytes, which appeared to be accompanied by the expression of TNFSF13B and OAS1 (Figure 13) indicating that monocytes may play a vital role in these two kinds of metabolic disorders in the peripheral blood of SLE patients.