We further exhibited that some cancer types expressed a higher ratio of up-regulated PTPs (such as pancreatic adenocarcinoma (PAAD) and diffuse large b-cell lymphoma (DLBC)), and other cancers had more down-regulated PTPs (such as adrenocortical carcinoma (ACC) and uterine carcinosarcoma (UCS)) (Figure 1D). Here, PTS is linked to pancreatic adenocarcinoma.