TGFB1 and idiopathic pulmonary fibrosis: A recent study found that EVs from healthy HBECs could reduce TGF-β-induced myofibroblast differentiation in vitro, and intratracheal administration of these EVs promoted collagen degradation in BLM-induced IPF by inhibiting the crosstalks between the TGF-β and Wnt pathways (84).