IFNB1 and infection: The mean concentrations of IFN-β, -λ1, and -λ2 in both groups of epithelial cells were detectable at 24 - 72 h after RV 16 inoculation, with peak induction observed at 48 h post-infection, showing patterns similar to RV 16 replication rates (Figures 2B, D, F and Supplementary Tables 2, 3 and Supplementary Figures 3).