CYP2B6 and immune system disorder: Moreover, recent case reports of ROS in which patients were examined for immune disorders showed no signs of immune disorders (anti-nuclear antibodies, antiphospholipid antibodies, lupus antibodies, antibodies to semicarbazide, adrenocortical autoantibodies, steroid cell autoantibodies, serum 21-hydroxylase, 17-hydroxylase, and P450 side-chain cleavage enzyme autoantibodies were all negative) (60–62).