OPRK1 and Cognitive impairment: The present study illustrates the action of the active ingredients—hexadecanoic acid, stigmasterol, beta-sitosterol, and angelicin—on the diabetic cognitive impairment-related proteins OPRK1, GABRA5, GABRP, and SCN3B that are responsible for the beneficial properties of the Shunaoxin pill on cognitive impairment in diabetic patients.