CXCL8 and cystic fibrosis: Another in vitro study found that PF prevented the further development of the inflammatory response in PAO1-induced IB3-1 CF bronchial epithelial cells by inhibiting the expression of the PAO1-dependent neutrophil chemokines interleukin-8 (IL-8), growth-regulating oncogene alpha (GRO-α) and GRO-γ, the adhesion molecule intercellular adhesion molecule (ICAM) 1 and the pro-inflammatory cytokine interleukin-6 (IL-6) (Nicolis et al., 2008).