It is well-known that the Raf/Mek/Erk cascade, which is one of the major Ras downstream signaling pathways, is involved in proliferation, apoptosis, cell cycle, invasion, migration, and metastasis of gastric cancer (Magnelli et al., 2020; Zhou et al., 2020) and is considered to be the compelling target for Ras-driven cancer therapy (Tatli and Dinler Doganay, 2021). This evidence concerns the gene MAP2K7 and cancer.