This further led to the release of proinflammatory cytokines such as IL-1, 6, 8, tumour TNF-α, nuclear factor kappa B (NF-κB) and monocyte chemoattractant protein-1 (MCP-1), resulting in permanent renal damage (Abdelrahman et al., 2005). The gene discussed is CCL2; the disease is neoplasm.