Muse cells that homed to the post-infarct area of a stroke model started elongating neurites and expressing progenitor markers NeuroD and Mash1 within 3 days, forming a network-like structure, and expressed maturity markers MAP2 and NeuN at 7 days (Uchida et al., 2017a; Sato et al., 2020). The gene discussed is ASCL1; the disease is Stroke.