BA could inhibit c-myc-induced glycolytic activation and inhibited protein expression of c-Myc, LDHA, and p-PDK1/PDK1 in MCF-7 and MDA-MB-231 cells in vitro and mice breast cancer model suggested that BA is a good candidate for the glycolysis inhibitor in vivo (Jiao et al., 2019). Here, PDK1 is linked to breast carcinoma.