Protein levels of GLUT1, PGK1, LDHA, and PKM2 were all decreased by N-methylhemeanthidine chloride (NMHC) in pancreatic cancer cell lines (AsPC-1, BxPC-3, and Mia PaCa-2) (Guo et al., 2014), resulting in a decrease in glucose metabolism. This evidence concerns the gene LDHA and familial pancreatic carcinoma.