(6) investigated glycemic and other metabolic effects of glucose-fructose co-ingestion (among other CHOs, this CHO composition (glucose+fructose) is contained in many juices, Figure 1) with glucose-only ingestion to maintain glycemia in physically active individuals with T1DM who participated in two 90-min iso-energetic continuous cycling sessions at 50% VO2max (without insulin adjustment). The gene discussed is INS; the disease is type 1 diabetes mellitus.