COL1A1 and osteogenesis imperfecta: Compared to BSA-matched controls, OI patients with COL1A1 mutation had greater internal diameters of MPA (1.83 versus 1.60 cm, P = 0.002), LAD (2.62 versus 2.11 cm, P < 0.001), LVEDd (3.90 versus 3.50 cm, P = 0.011), and lower LVEF (68.00% versus 71.74%, P = 0.008) (Table 4).