Our study demonstrated that higher serum corin at baseline predicted a higher risk of CVD events and stroke, but not CHD, in an unselected community-based population of Chinese adults, independent of conventional risk factors.PerspectivesCOMPETENCY IN MEDICAL KNOWLEDGE: Soluble corin has been found to predict the risk of cardiovascular events in patients with myocardial infarction and heart failure. The gene discussed is CORIN; the disease is heart failure.