Our qRT-PCR data revealed that sphingolipid metabolic key genes encoding enzymes: Cers2, Gba2, Gla, Asah1, Asah2, Acer2, Acer3, Neu3, Sgpp1, and Sphk1 were robustly upregulated in mRNA levels by the infection of C. sinensis. This evidence concerns the gene SPHK1 and infection.