We selected six Cuproptosis-related lncRNAs for validation, and we detected their expression levels in non-tumor brain tissues and glioma tissues, By using RT-qPCR assay, the expression level of AL158212.3,BASP1-AS1, LINC01537 showed an overall upward trend in non-tumor brain tissues, the expression level of AC099850.3,AC244453.3,FAM181A-AS1 showed an overall upward trend in glioma tissues. The gene discussed is FAM181A; the disease is glioma.