Exosomal hsa-miR 199-3p has the ability to enhance the proliferative nature of cancer by downregulating the NEDD4 level in neuroblastoma, indicating that exosomal hsa-miR199a-3p might be associated in the future development of novel therapeutic strategies for neuroblastoma (Ma et al., 2019). Here, NEDD4 is linked to neuroblastoma.