Beyond melanoma, increased expression of CD146 has been reported in more than ten types of tumors to date (Zabouo et al., 2009; Feng et al., 2012; Zeng et al., 2012; Tian et al., 2013; Wang and Yan, 2013; Li et al., 2014; Liang et al., 2017; Sechler et al., 2017). Here, MCAM is linked to melanoma.