MCAM and prostate adenocarcinoma: The results also demonstrated that CD146 is highly expressed in tumor tissues relative to normal tissues in many tumors, including head and neck squamous cell carcinoma (HNSC), prostate adenocarcinoma (PRAD), kidney renal papillary cell carcinoma (KIRP), KIRC, liver hepatocellular carcinoma (LIHC), thyroid carcinoma (THCA), and pheochromocytoma and paraganglia (PCPG) (Figure 1A).