NRP1 expression was negatively correlated with tumor purity (cor = -0.325, p = 3.27e-13), while positively related with B cells (partial.cor = 0.092, p = 4.53e-02), CD8+ cells (partial.cor = 0.32, p = 8.89e-13), CD4+ cells (partial.cor = 0.343, p = 1.56e-14), macrophages (partial.cor = 0.525, p = 3.59e-35), neutrophils (partial.cor = 0.474, p = 5.34e-28), and DCs (partial.cor = 0.533, p = 3.43e-36) in LUSC tumors (Supplementary Figure S1A). Here, CD4 is linked to neoplasm.