CALR closely interacted with PDIA3 (also known as ERp57) and prolyl 4-hydroxylase β polypeptide (P4HB, also known as PDIA1), which have been reported as prognostic markers in cervical cancer (Chung et al., 2013), hepatocellular carcinoma (Takata et al., 2016), glioma (Sun et al., 2013), and KIRC (Zhu et al., 2019). Here, P4HB is linked to central nervous system cancer.