Previous studies have shown that CALR is associated with various diseases, such as myeloproliferative neoplasms (MPNs) (Klampfl et al., 2013; Nangalia et al., 2013), neuroblastoma (Hsu et al., 2005), colorectal carcinoma (Peng et al., 2010), non-small cell lung carcinoma (NSCLC) (Fucikova et al., 2016), acute myeloid leukemia (AML) (Schardt et al., 2009), osteosarcoma (Zhang et al., 2017), and glioblastoma (Muth et al., 2016). The gene discussed is CALR; the disease is colorectal carcinoma.