In particular, a high CALR expression has been correlated with poor outcomes in gastric carcinoma (Chen et al., 2009), NSCLC (Liu et al., 2012), breast carcinoma (Lwin et al., 2010), pancreatic cancer (Matsukuma et al., 2016), neuroblastoma, bladder carcinoma, and mantle cell lymphoma (Chao et al., 2010). This evidence concerns the gene CALR and familial pancreatic carcinoma.