The prognostic module, OCM, contained genes that were already reported to be associated with ovarian cancer together with novel candidates, such as CDT1, CNIH4, CRLS1, LIMCH1, POC1A, and SNX13. The nucleosome enrichment analyses of novel candidate genes were carried out across samples including breast adenocarcinoma, chronic myelogenous leukemia, skin melanoma, and cervical carcinoma cell lines to enlighten the nucleosome distribution around TSSs. The gene discussed is CRLS1; the disease is cutaneous melanoma.