As mutations in STAT1 and IFNGR1 are known to be responsible for both AD and AR forms of mycobacteriosis, the heterozygous variants identified in these genes (STAT1 c.373–2A>C and IFNGR1 c.40G>A/p.(Val14Met) are the most promising causal candidates in this study. This evidence concerns the gene STAT1 and mycobacterial infectious disease.