The nucleotide sequence analysis of non-Hodgkin B-cell lymphoma, a hematopoietic malignancy, allowed the identification of an aberrant fusion gene of SRP9 conjoined with epoxide hydrolase 1 (EPHX1, encoded at the cytogenetic band 1q42.12) (20), suggesting that the mechanism that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols resulting in secretion from cells may be involved in this disease. This evidence concerns the gene EPHX1 and B-cell non-Hodgkin lymphoma.