Figure 3A shows high parenchymal CD4+ T cell inclusion in six samples, high CD8+ T cell inclusion in three samples, and high Treg inclusion in four samples. However, notable tumor parenchymal exclusion was seen at higher rates, with 13 samples meeting criteria for high CD4+ T cell exclusion, 23 samples for high CD8+ T cell exclusion, and 12 samples for high Treg exclusion. The gene discussed is CD8A; the disease is neoplasm.