GPBAR1 and central nervous system cancer: As shown in Figure 4, it was apparent that the high expression of TGR5 was related to poor prognosis of OS for cancers such as GBM (p = 0.0048), KIRP (p = 0.033), lower grade glioma (LGG) (p = 0.0028), thymoma (THYM) (p = 0.048), and uveal melanoma (UVM) (p = 0.004).