GPBAR1 and glioblastoma: Besides, we further found that a low expression of TGR5 also has better OS in GBM, KIRP, LGG, THYM, and UVM but a high expression related with better OS in CESC, MESO, SARC, and SKCM, which means that TGR5 may be an important indicator for predicting the prognosis of cancer patients.